The mechanism of loosening of cemented acetabular components in total hip arthroplasty: analysis of specimens retrieved at autopsy
…, LM KWONG, M Jasty, RC SEDLACEK… - Clinical Orthopaedics …, 1992 - journals.lww.com
Late aseptic loosening of cemented acetabular components is governed by the progressive,
three-dimensional resorption of the bone immediately adjacent to the cement mantle. This …
three-dimensional resorption of the bone immediately adjacent to the cement mantle. This …
The transmembrane CXC-chemokine ligand 16 is induced by IFN-γ and TNF-α and shed by the activity of the disintegrin-like metalloproteinase ADAM10
…, N Broadway, D Hartmann, R Sedlacek… - The Journal of …, 2004 - journals.aai.org
The novel CXC-chemokine ligand 16 (CXCL16) functions as transmembrane adhesion
molecule on the surface of APCs and as a soluble chemoattractant for activated T cells. In this …
molecule on the surface of APCs and as a soluble chemoattractant for activated T cells. In this …
[HTML][HTML] A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes
M Flemr, R Malik, V Franke, J Nejepinska, R Sedlacek… - Cell, 2013 - cell.com
In mammals, a single Dicer participates in biogenesis of small RNAs in microRNA (miRNA)
and RNAi pathways. In mice, endogenous RNAi is highly active in oocytes, but not in somatic …
and RNAi pathways. In mice, endogenous RNAi is highly active in oocytes, but not in somatic …
[HTML][HTML] CRISPR/Cas9 epigenome editing potential for rare imprinting diseases: a review
LA Syding, P Nickl, P Kasparek, R Sedlacek - Cells, 2020 - mdpi.com
Imprinting diseases (IDs) are rare congenital disorders caused by aberrant dosages of
imprinted genes. Rare IDs are comprised by a group of several distinct disorders that share a …
imprinted genes. Rare IDs are comprised by a group of several distinct disorders that share a …
[HTML][HTML] Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice
…, T Hatziioannou, J Prochazka, R Sedlacek… - Nature, 2021 - nature.com
Neutralizing antibodies that target the receptor-binding domain (RBD) of the SARS-CoV-2
spike protein are among the most promising approaches against COVID-19 1 , 2 . A bispecific …
spike protein are among the most promising approaches against COVID-19 1 , 2 . A bispecific …
Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells
10.7554/eLife.22187.001 Recently, we showed that generation of tumours in syngeneic mice
by cells devoid of mitochondrial (mt) DNA (ρ 0 cells) is linked to the acquisition of the host …
by cells devoid of mitochondrial (mt) DNA (ρ 0 cells) is linked to the acquisition of the host …
[PDF][PDF] Structural and functional basis of mammalian microRNA biogenesis by Dicer
…, R Sedlacek, C Bernecky, D O'Carroll, R Stefl… - Molecular Cell, 2022 - cell.com
MicroRNA (miRNA) and RNA interference (RNAi) pathways rely on small RNAs produced
by Dicer endonucleases. Mammalian Dicer primarily supports the essential gene-regulating …
by Dicer endonucleases. Mammalian Dicer primarily supports the essential gene-regulating …
[PDF][PDF] A cellular and spatial map of the choroid plexus across brain ventricles and ages
…, J Prochazka, M Prochazkova, R Sedlacek… - Cell, 2021 - cell.com
The choroid plexus (ChP) in each brain ventricle produces cerebrospinal fluid (CSF) and
forms the blood-CSF barrier. Here, we construct a single-cell and spatial atlas of each ChP in …
forms the blood-CSF barrier. Here, we construct a single-cell and spatial atlas of each ChP in …
Restoration of severely damaged endodontically treated premolars: The influence of the endo-core length on marginal integrity and fatigue resistance of lithium …
GT Rocca, R Daher, CM Saratti, R Sedlacek, T Suchy… - Journal of dentistry, 2018 - Elsevier
… Data and statistical analyses were performed with R software, version 2.15.2 (… (a) Frontal
view of the inner intaglio surface of the ceramic restoration (R). (b) Lateral view of the margin. …
view of the inner intaglio surface of the ceramic restoration (R). (b) Lateral view of the margin. …
Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein
…, A Franzetti-Pellanda, C Garzoni, R Sedlacek… - Science …, 2023 - science.org
Emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
diminishes the efficacy of vaccines and antiviral monoclonal antibodies. Continued development …
diminishes the efficacy of vaccines and antiviral monoclonal antibodies. Continued development …