SR proteins and splicing control 1569

…, BO Williams, G Mulligan, S Mukai, RT Bronson… - Genes …, 1996 - genesdev.cshlp.org
Bronson, Nicholas Dyson, Ed Harlow, and Tyler Jacks … Bronson, Nicholas Dyson, Ed
Harlow, David Beach, Robert A. Weinberg, and Tyler Jacks …

Segmental trisomy as a mouse model for Down syndrome.

…, EC Akeson, BS Harris, RT Bronson - Progress in clinical …, 1993 - europepmc.org
Mice trisomic for Chromosome (Chr) 16 have been used extensively as an animal model for
human Down Syndrome (Trisomy 21). This system has drawbacks, however: trisomy for all …

Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium

AY Nikitin, A Alcaraz, MR Anver, RT Bronson… - Cancer research, 2004 - AACR
… During the workshop, all cases were reviewed and discussed by the pathologist panel
using a multihead Nikon microscope and SPOT-RT-mediated projection microscopy. At the …

[HTML][HTML] Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

…, K Sasaki, K Deguchi, Y Shimizu, RT Bronson… - cell, 1997 - cell.com
A transcription factor, Cbfa1, which belongs to the runt-domain gene family, is expressed
restrictively in fetal development. To elucidate the function of Cbfa1, we generated mice with a …

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

AA Beg, WC Sha, RT Bronson, S Ghosh, D Baltimore - Nature, 1995 - nature.com
… Identical results were obtained when the RT-PCR analysis was done with independently …
(90 min; lanes 2 and 4) WT or RelA KO EFs was analysed by RT-PCR using lBß-specific …

[HTML][HTML] Identification of bronchioalveolar stem cells in normal lung and lung cancer

…, S Lawrence, I Babar, S Vogel, D Crowley, RT Bronson… - Cell, 2005 - cell.com
Injury models have suggested that the lung contains anatomically and functionally distinct
epithelial stem cell populations. We have isolated such a regional pulmonary stem cell …

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

…, D Sun, M Kaghad, N Walker, RT Bronson… - Nature, 1999 - nature.com
The p63 gene, a homologue of the tumour-suppressor p53 ( 1 – 5 ), is highly expressed in
the basal or progenitor layers of many epithelial tissues 1 . Here we report that mice …

Tumor spectrum analysis in p53-mutant mice

…, BO Williams, EM Schmitt, S Halachmi, RT Bronson… - Current biology, 1994 - cell.com
Background: The p53 tumor suppressor gene is mutated in a large percentage of human
malignancies, including tumors of the colon, breast, lung and brain. Individuals who inherit one …

Effects of an Rb mutation in the mouse

T Jacks, A Fazeli, EM Schmitt, RT Bronson, MA Goodell… - Nature, 1992 - nature.com
The retinoblastoma gene is mutated in several types of human cancer and is the best
characterized of the tumour-suppressor genes. A mouse strain has been constructed in which one …

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

EL Jackson, N Willis, K Mercer, RT Bronson… - Genes & …, 2001 - genesdev.cshlp.org
Adenocarcinoma of the lung is the most common form of lung cancer, but the cell of origin
and the stages of progression of this tumor type are not well understood. We have developed …