User profiles for P. Van Der Veken

Pieter Van der Veken

Professor of Medicinal Chemistry
Verified email at uantwerpen.be
Cited by 6635

Inhibitors of the purine salvage pathway: a valuable approach for antiprotozoal chemotherapy?

M Berg, P Van der Veken, A Goeminne… - Current medicinal …, 2010 - ingentaconnect.com
For many years, the purine salvage pathway of parasitic protozoa has been regarded as an
attractive chemotherapeutic target. Parasitic protozoa lack de novo synthesis and rely …

[HTML][HTML] ClpP protease, a promising antimicrobial target

…, K Goossens, IG Salado, P Van Der Veken… - International journal of …, 2019 - mdpi.com
… An analysis of the ClpP expression through the P. falciparum life cycle demonstrated
overexpression in the stages in which P. falciparum colony increases and infects red blood cells (…

[HTML][HTML] Molecular imaging of apoptosis: the case of caspase-3 radiotracers

…, S Stroobants, P Van der Veken… - International Journal of …, 2021 - mdpi.com
The molecular imaging of apoptosis remains an important method for the diagnosis and
monitoring of the progression of certain diseases and the evaluation of the efficacy of anticancer …

3‐methyl‐1, 2, 3‐butanetricarboxylic acid: An atmospheric tracer for terpene secondary organic aerosol

…, Y Gómez‐González, P Van der Veken… - Geophysical …, 2007 - Wiley Online Library
Highly oxygenated compounds assigned to be oxidation products of α‐pinene have recently
been observed in substantial concentrations in ambient aerosols. Here, we confirm the …

Hydroxydicarboxylic acids: Markers for secondary organic aerosol from the photooxidation of α-pinene

…, I Kourtchev, P Van der Veken… - Environmental …, 2007 - ACS Publications
Detailed organic analysis of fine (PM 2.5 ) rural aerosol collected during summer at K-puszta,
Hungary from a mixed deciduous/coniferous forest site shows the presence of polar …

Extended structure–activity relationship and pharmacokinetic investigation of (4-quinolinoyl) glycyl-2-cyanopyrrolidine inhibitors of fibroblast activation protein (FAP)

…, K Augustyns, P Van der Veken - Journal of medicinal …, 2014 - ACS Publications
… Substrates used in the IC 50 measurements were Ala-Pro-p-nitroanilide (2 mM) at pH 7.4
for FAP assays and Z-Gly-Pro-p-nitroanilide (0.25 mM) at pH 7.5 for PREP assays. DPPIV …

Selective inhibitors of fibroblast activation protein (FAP) with a (4-quinolinoyl)-glycyl-2-cyanopyrrolidine scaffold

…, K Augustyns, P Van der Veken - ACS medicinal …, 2013 - ACS Publications
Fibroblast activation protein (FAP) is a serine protease that is generally accepted to play an
important role in tumor growth and other diseases involving tissue remodeling. Currently …

Terpenylic acid and related compounds from the oxidation of α-pinene: Implications for new particle formation and growth above forests

…, R Vermeylen, P Van der Veken… - … science & technology, 2009 - ACS Publications
Novel secondary organic aerosol (SOA) products from the monoterpene α-pinene with unique
dimer-forming properties have been identified as lactone-containing terpenoic acids, ie, …

Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ

…, M Lahtela-Kakkonen, P Van der Veken… - Biochemical …, 2014 - Elsevier
The transcription factor NF-κB is one of the main players involved in inflammatory responses
during which NF-κB becomes rapidly activated. However to maintain homeostasis, this NF-…

A prolyl oligopeptidase inhibitor, KYP‐2047, reduces α‐synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease

…, M Gérard, P Van Der Veken… - British journal of …, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE The aggregation of α‐synuclein is connected to the pathology
of Parkinson's disease and prolyl oligopeptidase (PREP) accelerates the aggregation of …