User profiles for P. Van Der Veken
Pieter Van der VekenProfessor of Medicinal Chemistry Verified email at uantwerpen.be Cited by 6635 |
Inhibitors of the purine salvage pathway: a valuable approach for antiprotozoal chemotherapy?
M Berg, P Van der Veken, A Goeminne… - Current medicinal …, 2010 - ingentaconnect.com
For many years, the purine salvage pathway of parasitic protozoa has been regarded as an
attractive chemotherapeutic target. Parasitic protozoa lack de novo synthesis and rely …
attractive chemotherapeutic target. Parasitic protozoa lack de novo synthesis and rely …
[HTML][HTML] ClpP protease, a promising antimicrobial target
…, K Goossens, IG Salado, P Van Der Veken… - International journal of …, 2019 - mdpi.com
… An analysis of the ClpP expression through the P. falciparum life cycle demonstrated
overexpression in the stages in which P. falciparum colony increases and infects red blood cells (…
overexpression in the stages in which P. falciparum colony increases and infects red blood cells (…
[HTML][HTML] Molecular imaging of apoptosis: the case of caspase-3 radiotracers
…, S Stroobants, P Van der Veken… - International Journal of …, 2021 - mdpi.com
The molecular imaging of apoptosis remains an important method for the diagnosis and
monitoring of the progression of certain diseases and the evaluation of the efficacy of anticancer …
monitoring of the progression of certain diseases and the evaluation of the efficacy of anticancer …
3‐methyl‐1, 2, 3‐butanetricarboxylic acid: An atmospheric tracer for terpene secondary organic aerosol
…, Y Gómez‐González, P Van der Veken… - Geophysical …, 2007 - Wiley Online Library
Highly oxygenated compounds assigned to be oxidation products of α‐pinene have recently
been observed in substantial concentrations in ambient aerosols. Here, we confirm the …
been observed in substantial concentrations in ambient aerosols. Here, we confirm the …
Hydroxydicarboxylic acids: Markers for secondary organic aerosol from the photooxidation of α-pinene
…, I Kourtchev, P Van der Veken… - Environmental …, 2007 - ACS Publications
Detailed organic analysis of fine (PM 2.5 ) rural aerosol collected during summer at K-puszta,
Hungary from a mixed deciduous/coniferous forest site shows the presence of polar …
Hungary from a mixed deciduous/coniferous forest site shows the presence of polar …
Extended structure–activity relationship and pharmacokinetic investigation of (4-quinolinoyl) glycyl-2-cyanopyrrolidine inhibitors of fibroblast activation protein (FAP)
…, K Augustyns, P Van der Veken - Journal of medicinal …, 2014 - ACS Publications
… Substrates used in the IC 50 measurements were Ala-Pro-p-nitroanilide (2 mM) at pH 7.4
for FAP assays and Z-Gly-Pro-p-nitroanilide (0.25 mM) at pH 7.5 for PREP assays. DPPIV …
for FAP assays and Z-Gly-Pro-p-nitroanilide (0.25 mM) at pH 7.5 for PREP assays. DPPIV …
Selective inhibitors of fibroblast activation protein (FAP) with a (4-quinolinoyl)-glycyl-2-cyanopyrrolidine scaffold
…, K Augustyns, P Van der Veken - ACS medicinal …, 2013 - ACS Publications
Fibroblast activation protein (FAP) is a serine protease that is generally accepted to play an
important role in tumor growth and other diseases involving tissue remodeling. Currently …
important role in tumor growth and other diseases involving tissue remodeling. Currently …
Terpenylic acid and related compounds from the oxidation of α-pinene: Implications for new particle formation and growth above forests
…, R Vermeylen, P Van der Veken… - … science & technology, 2009 - ACS Publications
Novel secondary organic aerosol (SOA) products from the monoterpene α-pinene with unique
dimer-forming properties have been identified as lactone-containing terpenoic acids, ie, …
dimer-forming properties have been identified as lactone-containing terpenoic acids, ie, …
Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ
…, M Lahtela-Kakkonen, P Van der Veken… - Biochemical …, 2014 - Elsevier
The transcription factor NF-κB is one of the main players involved in inflammatory responses
during which NF-κB becomes rapidly activated. However to maintain homeostasis, this NF-…
during which NF-κB becomes rapidly activated. However to maintain homeostasis, this NF-…
A prolyl oligopeptidase inhibitor, KYP‐2047, reduces α‐synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease
…, M Gérard, P Van Der Veken… - British journal of …, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE The aggregation of α‐synuclein is connected to the pathology
of Parkinson's disease and prolyl oligopeptidase (PREP) accelerates the aggregation of …
of Parkinson's disease and prolyl oligopeptidase (PREP) accelerates the aggregation of …