User profiles for P. A. Goy

Pierre-Alexis Goy

Research Fellow, National University of Singapore
Verified email at u.nus.edu
Cited by 353

[PDF][PDF] Therapeutic targeting of RNA splicing catalysis through inhibition of protein arginine methylation

JY Fong, L Pignata, PA Goy, KC Kawabata, SCW Lee… - Cancer cell, 2019 - cell.com
Cancer-associated mutations in genes encoding RNA splicing factors (SFs) commonly
occur in leukemias, as well as in a variety of solid tumors, and confer dependence on wild-type …

Inhibition of bacterial and fungal plant pathogens by thionins of types I and II

A Molina, PA Goy, A Fraile, R Sánchez-Monge… - Plant Science, 1993 - Elsevier
Thionins are cysteine-rich, 5 kDa polypeptides which are active against plant pathogens.
Thionins of type I, from the endosperms of wheat (Wα1, Wα2, Wβ) and barley (Bα, Bβ), and of …

Accumulation of scopoletin is associated with the high disease resistance of the hybrid Nicotiana glutinosa x Nicotiana debneyi

PA Goy, H Signer, R Reist, R Aichholz, W Blum… - Planta, 1993 - Springer
The high disease resistance of the amphidiploid hybrid of Nicotiana glutinosa x Nicotiana
debneyi is associated with high constitutive levels of two phenolic compounds as analysed by …

[HTML][HTML] Agrin-Matrix Metalloproteinase-12 axis confers a mechanically competent microenvironment in skin wound healing

…, M Bilton, CK Huang, MH Nai, K Njah, PA Goy… - Nature …, 2021 - nature.com
… The average traction stress of leader cells after 6 h post-migration was ~4.67 Pa, which
was reduced by ~32% upon Agrin depletion. Also, we mapped the velocity field using particle …

MBNL1 alternative splicing isoforms play opposing roles in cancer

T Tabaglio, DHP Low, WKL Teo, PA Goy… - Life science …, 2018 - life-science-alliance.org
… This work was supported by A*STAR Graduate Award–Singapore INternational Graduate
Award (AGA-SINGA) fellowship to T Tabaglio and PA Goy. E Guccione acknowledges support …

Identification of quinolinols as activators of TEAD-dependent transcription

…, H Karatas, SR Bharath, SM Guéret, PA Goy… - ACS Chemical …, 2019 - ACS Publications
The transcriptional co-regulators YAP (Yes-associated protein) and TAZ (transcriptional
coactivator with PDZ-binding motif) are the vertebrate downstream effectors of the Hippo …

Evidence for a third structural class of β-1, 3-glucanase in tobacco

G Payne, E Ward, T Gaffney, PA Goy, M Moyer… - Plant molecular …, 1990 - Springer
Glucan endo-1,3-β-glucosidases (β-1,3-glucanases) have been implicated in several
developmental processes and they may also play a direct role in the plant's defense against fungal …

Mitchell-Riley syndrome iPSCs exhibit reduced pancreatic endoderm differentiation due to a mutation in RFX6

…, J Strutt, A Kumar, LB Tomaz, PA Goy… - …, 2020 - journals.biologists.com
Mitchell-Riley syndrome (MRS) is caused by recessive mutations in the regulatory factor X6
gene (RFX6) and is characterised by pancreatic hypoplasia and neonatal diabetes. To …

The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons

MKY Seah, Y Wang, PA Goy, HM Loh, WJ Peh… - …, 2019 - journals.biologists.com
Global epigenetic reprogramming is vital to purge germ cell-specific epigenetic features to
establish the totipotent state of the embryo. This process transpires to be carefully regulated …

Resistance to disease in the hybrid Nicotiana glutinosa x Nicotiana debneyi is associated with high constitutive levels of β-1, 3-glucanase, chitinase, peroxidase and …

PA Goy, G Felix, JP Metraux, F Meins Jr - Physiological and Molecular Plant …, 1992 - Elsevier
The tobacco hybrid Nicotiana glutinosa × Nicotiana debneyi is much more resistant than either
parental species to tobacco mosaic virus, tobacco necrosis virus, Pseudomonas syringae …