User profiles for N. Hosoya

Naoki Hosoya

Shibaura Institute of Technology, Full Professor
Verified email at shibaura-it.ac.jp
Cited by 1621

Targeting DNA damage response in cancer therapy

N Hosoya, K Miyagawa - Cancer science, 2014 - Wiley Online Library
Cancer chemotherapy and radiotherapy are designed to kill cancer cells mostly by inducing
DNA damage. DNA damage is normally recognized and repaired by the intrinsic DNA …

A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays

Y Nannya, M Sanada, K Nakazaki, N Hosoya, L Wang… - Cancer research, 2005 - AACR
… -to-noise (S/N) ratios and the use of an optimized reference. The raw S/N ratios were improved
by … of multiple normal references with the highest S/N ratios, in combination with the data …

A review of the literature on the efficacy of mineral trioxide aggregate in conservative dentistry

N Hosoya, T Takigawa, T Horie, H Maeda… - Dental materials …, 2019 - jstage.jst.go.jp
The aim of this literature review was to assess the clinical performance of MTA to establish
the evidence level for its effectiveness in vital pulp therapy, perforation repair, and retrograde …

Nondigestibility of a new sweetener,“Neosugar,” in the rat

T Oku, T Tokunaga, N Hosoya - The Journal of nutrition, 1984 - Elsevier
… & Hosoya, N. (1976) Effect of dietary carbohydrate on rat in testinal … & Hosoya, N. (1972)
Me tabolism of circulating maltose in … & Hosoya, N. (1982) Mechanism of inhibitory effect of …

[HTML][HTML] Mouse jagged1 physically interacts with notch2 and other notch receptors: assessment by quantitative methods

K Shimizu, S Chiba, K Kumano, N Hosoya… - Journal of Biological …, 1999 - ASBMB
… Scatchard analysis of mJagged1 binding to BaF3 cells and to the soluble Notch2 protein
demonstrated dissociation constants of 0.4 and 0.7 nm, respectively, and that the number of …

Changes in enamel surface roughness and adhesion of Streptococcus mutans to enamel after vital bleaching

N Hosoya, K Honda, F Iino, T Arai - Journal of Dentistry, 2003 - Elsevier
Objectives. The purpose of this in vitro study was to observe the influence of vital bleaching
on changes to the enamel surface and adhesion of Streptococcus mutans to tooth enamel. …

Effects of calcium hydroxide on physical and sealing properties of canal sealers

N Hosoya, H Kurayama, F Iino… - International endodontic …, 2004 - Wiley Online Library
… Particularly large influences were observed for the combinations of Canals and Canals-N
with reagent Ca(OH) 2 . Decreases of 53.51 min with Canals and 54.96 min with Canals-N

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2

K Shimizu, S Chiba, N Hosoya, K Kumano… - … and cellular biology, 2000 - Taylor & Francis
… We confirmed that the MC and N fractions were correctly fractionated using antibodies …
seen in the N fraction and was considered to be a contamination into the N fraction. (Fig. 5A, cf. …

[HTML][HTML] Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia

…, K Sasaki, K Mitani, N Hosoya, N Hiramoto… - Nature …, 2021 - nature.com
Blast crisis (BC) predicts dismal outcomes in patients with chronic myeloid leukaemia (CML).
Although additional genetic alterations play a central role in BC, the landscape and …

Bolt loosening analysis and diagnosis by non-contact laser excitation vibration tests

F Huda, I Kajiwara, N Hosoya, S Kawamura - Mechanical Systems and …, 2013 - Elsevier
… force of 12,260 N is 5.5 cm to 15 cm, and it is 5.5 cm to 13.5 cm, 5.5 cm to 13 cm, 5.5 cm to
12 cm, and 5.5 cm to 9.5 cm for pretension forces of 10,000 N, 9000 N, 7500 N, and 5000 N, …