User profiles for L. F. Ng
Lin Feng NgFaculty of Mechanical Engineering, Universiti Teknologi Malaysia Verified email at utm.my Cited by 864 |
[HTML][HTML] WNT signaling in disease
Developmental signaling pathways control a vast array of biological processes during
embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and …
embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and …
[HTML][HTML] Deceptively simple but simply deceptive–Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects
The nematode worm Caenorhabditis elegans (C. elegans) is increasingly popular as a
model organism for aging studies as well as for testing antioxidants and other compounds for …
model organism for aging studies as well as for testing antioxidants and other compounds for …
Caenorhabditis elegans: What We Can and Cannot Learn from Aging Worms
Significance: The nematode Caenorhabditis elegans is a widely used model organism for
research into aging. However, nematodes diverged from other animals between 600 and …
research into aging. However, nematodes diverged from other animals between 600 and …
[HTML][HTML] The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease
β-Amyloid (Aβ)-induced toxicity and oxidative stress have been postulated to play critical
roles in the pathogenic mechanism of Alzheimer disease (AD). We investigated the in vivo …
roles in the pathogenic mechanism of Alzheimer disease (AD). We investigated the in vivo …
Hydrogen Sulfide Is an Endogenous Regulator of Aging in Caenorhabditis elegans
Aims: To investigate the role of endogenous hydrogen sulfide (H 2 S) in the control of aging
and healthspan of Caenorhabditis elegans. Results: We show that the model organism, C. …
and healthspan of Caenorhabditis elegans. Results: We show that the model organism, C. …
[HTML][HTML] Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model
Alzheimer Disease (AD) is a progressive neurological disorder characterized by the
deposition of amyloid beta (Aβ), predominantly the Aβ 1–42 form, in the brain. Mitochondrial …
deposition of amyloid beta (Aβ), predominantly the Aβ 1–42 form, in the brain. Mitochondrial …
[PDF][PDF] Drug synergy slows aging and improves healthspan through IGF and SREBP lipid signaling
There is growing interest in pharmacological interventions directly targeting the aging process.
Pharmacological interventions against aging should be efficacious when started in adults …
Pharmacological interventions against aging should be efficacious when started in adults …
Ageing in nematodes: do antioxidants extend lifespan in Caenorhabditis elegans?
Antioxidants are often investigated as a promising strategy for extending lifespan. Accordingly,
there is significant interest in novel antioxidant compounds derived from natural sources …
there is significant interest in novel antioxidant compounds derived from natural sources …
[HTML][HTML] Mitochondrial Changes in Ageing Caenorhabditis elegans – What Do We Learn from Superoxide Dismutase Knockouts?
One of the most popular damage accumulation theories of ageing is the mitochondrial free
radical theory of ageing (mFRTA). The mFRTA proposes that ageing is due to the …
radical theory of ageing (mFRTA). The mFRTA proposes that ageing is due to the …
Tensile and impact properties of cost‐effective hybrid fiber metal laminate sandwich structures
S Dhar Malingam, FA Jumaat, LF Ng… - Advances in polymer …, 2018 - Wiley Online Library
Hybrid composite materials, which combine two or more types of fiber in a single matrix,
have currently drawn the interest of researchers. This research investigates the tensile and …
have currently drawn the interest of researchers. This research investigates the tensile and …