Local bending phenomena can be predicted by elastic models that incorporate sequence-dependent
anisotropic-bendability (SDAB). SDAB models consider DNA to be an initially …

… In the three-modifications models, i, j, and k are chosen to cover all combinations of three …
I Chepelev, G Wei, Q Tang, K Zhao, Detection of single nucleotide variations in expressed …

Cancer is a disease potentiated by mutations in somatic cells. Cancer mutations are not
distributed uniformly along the human genome. Instead, different human genomic regions vary …

In mammals, a single Dicer participates in biogenesis of small RNAs in microRNA (miRNA)
and RNAi pathways. In mice, endogenous RNAi is highly active in oocytes, but not in somatic …

Biological insights can be obtained through computational integration of genomics data sets
consisting of diverse types of information. The integration is often hampered by a large …

Background PSAIA (Protein Structure and Interaction Analyzer) was developed to compute
geometric parameters for large sets of protein structures in order to predict and investigate …

… The average value of a particular feature k was calculated as: where i was the ordered
number of a residue in the window of N = 9 residues. The secondary structure information was …

Initiation of zygotic transcription in mammals is poorly understood. In mice, zygotic transcription
is first detected shortly after pronucleus formation in 1‐cell embryos, but the identity of the …

… To create the Pfa-2 dataset, the columns I, K, AB and AD were averaged to obtain an mRNA
abundance for the trophozoite, Q and AJ for the merozoite; column AO provided values for …

The WWW servers at http://www.icgeb.trieste.it/dna/ are dedicated to the analysis of user-submitted
DNA sequences; plot.it creates parametric plots of 45 physicochemical, as well as …