[PDF][PDF] Selective laminin-directed differentiation of human induced pluripotent stem cells into distinct ocular lineages

…, T Okubo, Y Kudo, T Katayama, Y Ishikawa, J Toga… - Cell reports, 2018 - cell.com
The extracellular matrix plays a key role in stem cell maintenance, expansion, and
differentiation. Laminin, a basement membrane protein, is a widely used substrate for cell culture …

[HTML][HTML] Phosphorylated intrinsically disordered region of FACT masks its nucleosomal DNA binding elements

Y Tsunaka, J Toga, H Yamaguchi, S Tate… - Journal of Biological …, 2009 - ASBMB
FACT is a heterodimer of SPT16 and SSRP1, which each contain several conserved regions
in the primary structure. The interaction of FACT with nucleosomes induces chromatin …

[HTML][HTML] Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells

R Ohta, A Niwa, Y Taniguchi, NM Suzuki, J Toga… - Scientific reports, 2016 - nature.com
Obtaining highly purified differentiated cells via directed differentiation from human pluripotent
stem cells (hPSCs) is an essential step for their clinical application. Among the various …

ITU-T standardization activities for interactive multimedia communications on packet-based networks: H. 323 and related recommendations

J Toga, J Ott - Computer Networks, 1999 - Elsevier
Toga develops standards and standards-based products within ITU-T, ETSI, IETF, and IMTC.
He is Editor of the ITU-T documents, “H.323 Implementers Guide” and “Recommendation H.…

[PDF][PDF] Cell-type-specific adhesiveness and proliferation propensity on laminin isoforms enable purification of iPSC-derived corneal epithelium

…, T Katayama, Y Ishikawa, Y Kobayashi, J Toga… - Stem Cell Reports, 2020 - cell.com
A treatment for intractable diseases is expected to be the replacement of damaged tissues
with products from human induced pluripotent stem cells (hiPSCs). Target cell purification is a …

Laminin γ1 C-terminal Glu to Gln mutation induces early postimplantation lethality

…, Y Taniguchi, I Nakano, J Toga… - Life Science …, 2018 - life-science-alliance.org
J is magnified in K. The open diamonds in I indicate the blood sinus. The asterisks in I and J
… (J) Genotypes of offspring obtained from mating between Lamc1 cEQ/+ female and Tie2-cre;…

Probing the acidic residue within the integrin binding site of laminin-511 that interacts with the metal ion-dependent adhesion site of α6β1 integrin

…, S Li, M Takizawa, E Oonishi, J Toga… - Biochemical and …, 2017 - Elsevier
Laminins are major cell-adhesive proteins of basement membranes that interact with integrins
in a divalent cation-dependent manner. Laminin-511 consists of α5, β1, and γ1 chains, of …

Mapping cortical change in Alzheimer's disease, brain development, and schizophrenia

…, Y Wang, TGM Van Erp, TD Cannon, AW Toga - Neuroimage, 2004 - Elsevier
This paper describes algorithms that can identify patterns of brain structure and function
associated with Alzheimer's disease, schizophrenia, normal aging, and abnormal brain …

Dental treatment and demand for services in a Veterans Administration nursing home care unit

…, LC Niessen, CJ Toga - Journal of Public Health …, 1984 - Wiley Online Library
Planning the provision of dental care in nursing homes requires evaluation of both dental
needs and demand for services. Dental treatment needs have been documented for residents …

Ways toward an early diagnosis in Alzheimer's disease: the Alzheimer's Disease Neuroimaging Initiative (ADNI)

…, CR Jack, W Jagust, JQ Trojanowski, AW Toga… - Alzheimer's & …, 2005 - Elsevier
With the increasing life expectancy in developed countries, the incidence of Alzheimer’s
disease (AD) and thus its socioeconomic impact are growing. Increasing knowledge over the …