User profiles for J. Brion

Jean-Pierre Brion

professeur, Université Libre de Bruxelles
Verified email at ulb.ac.be
Cited by 14794

[HTML][HTML] What is the evidence that tau pathology spreads through prion-like propagation?

…, E Mandelkow, L Buée, M Goedert, JP Brion - Acta neuropathologica …, 2017 - Springer
Emerging experimental evidence suggests that the spread of tau pathology in the brain in
Tauopathies reflects the propagation of abnormal tau species along neuroanatomically …

Neurofibrillary tangles and Alzheimer's disease

JP Brion - European neurology, 1998 - karger.com
… 17 Probst A, Anderton BH, Brion JP, Ulrich J: Senile plaque neurites fail to demonstrate
antipaired helical filaments and anti-microtubuleassociated protein tau immunoreactive proteins …

[HTML][HTML] PICALM and Alzheimer's disease: an update and perspectives

…, AC Kosa, E Doeraene, L Lopez Gutierrez, JP Brion… - Cells, 2022 - mdpi.com
Genome-wide association studies (GWAS) have identified the PICALM (Phosphatidylinositol
binding clathrin-assembly protein) gene as the most significant genetic susceptibility locus …

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the …

DP Hanger, K Hughes, JR Woodgett, JP Brion… - Neuroscience …, 1992 - Elsevier
… and Rebhun, LI, The distribution of tau in the mammalian central nervous system, J. Cell
Biol… tangles recognize a synthetic phosphopeptide, J. Neurochem., 54 (1990) 1548-1555. …

Ozone UV spectroscopy. II. Absorption cross-sections and temperature dependence

…, J Charbonnier, C Parisse, A Chakir, J Brion - Journal of atmospheric …, 1995 - Springer
Absolute absorption cross-sections of ozone have been measured at five temperatures (218–295
K) in the UV wavelength region corresponding to the Hartley and Huggins bands (195–…

Increased level of active GSK‐3β in Alzheimer's disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration

K Leroy, Z Yilmaz, JP Brion - Neuropathology and applied …, 2007 - Wiley Online Library
The somatodendritic accumulation of hyperphosphorylated tau proteins is an early event
preceding the appearance of neurofibrillary tangles (NFT) in Alzheimer’s disease (AD) and …

Ozone UV spectroscopy I: Absorption cross-sections at room temperature

…, J Brion, J Charbonnier, J Malicet - Journal of Atmospheric …, 1992 - Springer
Because of the importance of the absorption cross-sections of ozone in the atmosphere, we
give a new set of data at ambient temperature for the whole spectral region within the 195–…

Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor …

…, A Bretteville, K Leroy, S Bégard, JP Brion… - The American journal of …, 2006 - Elsevier
Tau transgenic mice are valuable models to investigate the role of tau protein in Alzheimer's
disease and other tauopathies. However, motor dysfunction and dystonic posture interfering …

Autoimmune and inflammatory manifestations occur frequently in patients with primary immunodeficiencies

…, C Briandet, JP Brion, C Brito, J Brouard… - Journal of Allergy and …, 2017 - Elsevier
Background Primary immunodeficiencies (PIDs) are inherited diseases associated with a
considerable increase in susceptibility to infections. It is known that PIDs can also predispose …

Neurofibrillary tangles of Alzheimer's disease: an immunohistochemical study.

JP Brion, AM Couck, E Passareiro… - Journal of …, 1985 - europepmc.org
The reactivity of neurofibrillary tangles (NFT) of Alzheimer's disease with several antisera
has been studied by immunocytochemistry. They were heavily labelled by an antiserum …