Viperin links lipid bodies to immune defense

Xiaomo Jiang; Zhijian J Chen

doi:10.1016/j.immuni.2011.03.012

Viperin links lipid bodies to immune defense

Immunity. 2011 Mar 25;34(3):285-7. doi: 10.1016/j.immuni.2011.03.012.

Authors

Xiaomo Jiang¹, Zhijian J Chen

Affiliation

¹ Department of Molecular Biology, University of Texas Southwestern Medical Center Dallas, TX 75390-9148, USA.

Abstract

Viperin is an interferon-stimulated gene that exerts antiviral effects. In this issue of Immunity, Saitoh et al. (2011) uncovered an unexpected function of Viperin and lipid bodies in interferon induction by Toll-like receptors, specifically in plasmacytoid dendritic cells.

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