Cancer Cell
Volume 31, Issue 6, 12 June 2017, Pages 771-789.e6
ArticleKupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
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Graphical Abstract
Keywords
intrahepatic cholangiocarcinoma
reactive oxygen species
Kupffer cell
mitochondrial dysfunction
Tnf
JNK
pro-inflammatory niche
cholastasis
unfolded protein response
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